Research Technician: Carnegie Institution for Science

Organization: The Kostova Lab
Carnegie Institute for Science
Department of Embryology
Date Posted: 3/18/2022
City: Baltimore
State: Maryland
Primary Category: Technician
Type of Position: Research Tecnician

Description & Details:

The Kostova laboratory at Carnegie’s Department of Embryology in Baltimore is searching for a full-time research technician. This is a great opportunity to work directly with a principal investigator using cutting edge technologies, and an exciting model organism (zebrafish!) to answer fundamental questions of cell biology. Ideal candidates should have a B.S. in Biology or related field, experience in modern molecular biology techniques, and a strong work ethic.

We are investigating the fundamental question of how cells respond when their ribosomes break down, and how defects in the translation apparatus lead to complex disease. The ribosome is one the most complex and long-lived molecular machines in the cell and the presence of functional ribosomes is essential to live. Ribosome damage has been recently linked to complex human diseases, such as cancer and neurodegeneration. We use cutting-edge technology, such as CRISPR-mediated genome editing to model ribosome defects in zebrafish, and map the molecular pathways that ensure ribosome integrity.

We are looking for a highly motivated individual with strong organizational skills to join our team and help explore these novel areas of biology.

Key Responsibilities:

  • Generate and maintain transgenic zebrafish lines
  • Molecular biology techniques, such as ribosome purification, in vitro translation system, western blotting, molecular cloning, etc.
  • Organize and maintain lab databases (plasmids, oligos, reagents, cell lines, etc.)

Qualifications:

Requirements:

  • B.S. in Biology (or equivalent)
  • Strong interpersonal skills and ability to work as part of a team

Preferred Skills:

  • Zebrafish work
  • Modern molecular biology techniques, e.g., DNA/RNA purification, cDNA synthesis, qPCR, plasmid cloning, SDS­PAGE, and Western blotting
  • Great organizational skills
  • Excellent written and oral communication skills

To Apply:

If interested please send the following documents to kostova@carnegiescience.edu:

  • Cover letter
  • Curriculum Vitae
  • Academic transcript
  • Recommendation letters (at least 2)
 
 

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