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Janelia Research Campus
Howard Hughes Medical Institute (HHMI)
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Description & Details:
The Research Specialist in Aquatics will be a pivotal member of the vivarium team with a focus on creating new genetically modified lines of zebrafish and danionella. This role will bridge shared resources and research labs to streamline development of transgenic fish species. The ideal candidate will possess critical thinking, expertise in zebrafish genetics, and hands-on skills with genetically modified zebrafish lines that facilitate high throughput line creation, maintenance, and cryopreservation.
What You'll Do
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Run the Aquatics pipeline to create and maintain new genetically modified strains of zebrafish, Danionella, and other aquatic organisms used in research at Janelia.
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Independently organize the workload for microinjections, fluorescent screening, fin clipping for genotyping, cryopreservation, and IVF.
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Perform microinjections, fluorescent screening, fin clipping, cryopreservation, and IVF.
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Train Aquatics staff and researchers on microinjections, fluorescent screening, fin clipping, cryopreservation, and IVF.
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Use established computer database to keep track of transgenic fish colonies.
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Work closely with labs and other shared resources on the development of materials used for gene modifications.
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Interface with labs and other shared resources to troubleshoot challenges with successful generation and screening of genetically modified aquatic organisms.
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Communicate with researchers, line creation project manager, and supervisor on the schedule and status of line generation, changes with breeding colony status, and other updates related to services provided for the creation and maintenance of genetically modified aquatic organisms.
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May assist the Aquatics team with husbandry, filtration maintenance, or other duties in the department not related to the creation and maintenance of genetically modified aquatic organisms.
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May work weekends and holidays.
Qualifications:
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Master’s degree and two years of related experience or Bachelor’s degree and six years of related experience.
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Demonstrated proficiency in the creation of genetically modified aquatic organisms.
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Demonstrated proficiency with microinjections of zebrafish embryos (including both cell and yolk injections), use of fluorescent microscopes for phenotyping fish lines, fin clipping, cryopreservation, and IVF.
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In-depth knowledge and the ability to effectively communicate on modern genome engineering techniques in aquatic organisms and the hands-on procedures for the care and use of zebrafish in research.
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In-depth knowledge of zebrafish anatomy and anatomical features.
To Apply:
Apply here
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