PhD Fellowship/Scholarship: Aarhus University

Organization: Aarhus University
Date Posted: 12/10/2021
City: Aarhus
Country: Denmark
Primary Category: Research
Type of Position: PhD Fellowship/Scholarship

 

Description and Details:

Applications are invited for a Ph.D. fellowship/scholarship at Graduate School of Natural Sciences, Aarhus University, Denmark, within the Molecular Biology and Genetics programme. The position is available from May 2022 or later.

Title of the Ph.D. project

"Extracellular RNA: Cell-to-Cell Communication over the Bloodstream"

Extracellular vesicles (EVs) are a new frontier in cell-to-cell communication that is distinct from the canonical lock-and-key principle of signalling by secretory factors such as cytokines and hormones. Of particular interest among EVs' biomolecular cargo is non-coding RNA capable of regulating gene expression in the recipient cells.

A Hallas-Møller Emerging Investigator grant from Novo Nordisk Foundation will support two Ph.D. positions in the coming years for a project on extracellular RNA biology. For this call, we are looking for a Ph.D. candidate on the exploratory phase of the project to identify extracellular RNA that plays a role in intercellular communication.

Our research group employs zebrafish as a model organism for studying blood-borne EVs in a cell type-specific manner. In this project, we aim to decode the RNA languages exchanged between macrophages and endothelial cells under pathophysiological conditions e.g. inflammation during wound angiogenesis.

As an integral part of the project, you will start by learning our zebrafish model of innate immunity through real-time imaging and four-dimensional analysis of cells in live embryos. You will also acquire skills in (cryo-) electron microscopy for tracing the biological fate of EVs. In parallel with the imaging studies, you will carry out bioinformatic analysis of RNA sequencing data to explore extracellular RNA in search of novel therapeutic targets.

For more information about our work, please visit the group webpage (https://mbg.au.dk/yuya-hayashi/).

Qualifications:

The Graduate School of Natural Sciences at Aarhus University is looking for a number of bright, enthusiastic and ambitious candidates who are interested in pursuing a Ph.D. education. The University is located in Aarhus, Denmark, which provides international students with a safe and stable environment, a high standard of living and a wealth of social opportunities.

Besides having an excellent reputation that enables our Ph.D. graduates to find outstanding employment prospects, Aarhus University offers attractive working conditions, research support and campus resources. Read more about all the benefits at the university webpage (https://international.au.dk).

Applications are accepted from college students and graduates with an academic record corresponding to a Master’s degree. Experience in zebrafish research or extracellular vesicles is preferred.

How to Apply

Please read the official announcement from the Graduate School of Natural Sciences, Aarhus University (https://phd.nat.au.dk/for-applicants/open-calls/february-2022/extracellular-rna-cell-to-cell-communication-over-the-bloodstream/).

This announcement is part of "February 2022 Call" with deadline 1 February 2021 at midnight (23.59 CET). 

Enquiries regarding the Ph.D. project: please contact Assistant Professor Yuya Hayashi (yuya.hayashi@mbg.au.dk).

 

 
 

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