Postdoctoral Position: Genetic Modelling of Vascular Anomalies in Zebrafish

The Department of Biochemistry & Molecular Biology
Cumming School of Medicine
University of Calgary

Description & Details:

Area: Genetic Modelling of Vascular Anomalies in Zebrafish
Duration: 2 years, extendible
Start Date: November 1, 2020
Salary: $50,000 per year plus benefits (negotiable depending on experience)

The Department of Biochemistry and Molecular Biology in the Cumming School of Medicine at the University of Calgary is accepting applications for a Postdoctoral Scholar in Genetic Modelling of Vascular Anomalies in Zebrafish.

We are looking for a creative, motivated postdoc to conduct independent research on the genetic basis of arteriovenous malformation and vascular overgrowths. Our lab models human genetic mutations leading to vascular anomalies in the zebrafish model so that we can understand the mechanism of disease, identify inhibitors and understand the interactions between genetic and mechanical (mechanobiology) inputs into vessel formation and homeostasis. This project will focus on the MAP kinase signaling pathway in vascular biology.

The postdoc will use molecular biology skills to create molecular constructs, conduct state of the art microscopy (Zeiss LSM 880, TEM and other techniques), knockout (CRISPR), gain of function (transgenic) techniques to probe the biology associated vascular malformations. The postdoc will collaborate with other members of the lab and be part of a vibrant developmental biology and genetics with access to all state of the art equipment necessary for the project.

Qualifications:

• A PhD, with 2 years or less of post-PhD research
• Demonstrated excellence in the form of peer reviewed publications
• The candidate will have strong molecular biology (cloning) skills and be familiar with CRISPR
• Microscopy experience strongly preferred
• Developmental biology experience in any model, but especially zebrafish is desired
• Creative thinking, strong interpersonal and leadership skills, and excellent time management skills are required as this is an independent research project
• Candidates with diverse backgrounds are encouraged to apply. Preference will be given to Canadian citizens and permanent residents of Canada. International trainees currently located in Canada are encouraged to apply

To Apply: Please send the following documents to: Dr. Sarah Childs, schilds@ucalgary.ca. 

1. Your CV
2. The names and contact details of 3 references
3. A statement (no more than one page) of your reason for interest in this position, including how your experience and skills would support the proposed project

To learn more about postdoctoral scholar opportunities at the University of Calgary and all we have to offer, view our Postdoc Careers website. For more information about the Cumming School of Medicine visit Careers in the Cumming School of Medicine.